Saturday, 7 October 2017

Ideal Properties of Antacids

An ideal antacid should not have any side effects other than its main action of neutralizing gastric acid. For example it should not have a constipating or Laxative effect. It should not cause, if absorbed, systemic alkalosis (in this condition the pH of the body fluids and tissues is high). It should not cause precipitation of phosphate I the gastrointestinal tract and depletion of phosphorus in the body. It should not also interfere with the absorption of other drugs such as tetracycline from the gut. It should not also delay the absorption of drugs which are weak acids or speed up the absorption of basic drugs. This happens when the pH of the gastric contents is raised.

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