Saturday, 7 October 2017

Effect of pH on gastric secretion

The gastric secretions in the stomach strive to maintain a pH of 2 to 5. Pepsin, a digestive enzyme, is activated at a pH of 2, and the acid-pepsin complex of gastric secretions can cause mucosal damage. If the pH of gastric secretions increases to 5, the activity of pepsin declines. 

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