Friday 2 June 2017

Disintegration test for Tablets:
All tablets must pass a test for disintegration except Chewable tablets and some extended release tablets
Tablets must disintegrate in the time set in the individual monograph, usually 30 min., but varying from 2 min for nitroglycerin sublingual tablets to up to 4 hrs for buccal tablets.

The end point of the test (i.e. complete disintegration) is achieved when no tablet fragments remain on the screen (fragments of coating may remain).

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