Disintegration test for Tablets:
All tablets must pass a test for disintegration except
Chewable tablets and some extended release tablets
Tablets must disintegrate in the time set in the individual
monograph, usually 30 min., but varying from 2 min for nitroglycerin sublingual
tablets to up to 4 hrs for buccal tablets.
The end point of the test (i.e. complete disintegration) is
achieved when no tablet fragments remain on the screen (fragments of coating
may remain).
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