Friday, 2 June 2017

Disintegration test for Enteric coated tablets: Enteric coated tablets are similarly tested except that the tablets are tested first in the simulated gastric fluid (0.1N HCl) for specific time (2hr in B.P.) for a positive test, after which no signs of disintegration, cracking or softening must be seen, followed by immersion in simulated intestinal fluid (Phosphate buffer pH 6.8) for the time stated in the individual monograph, during which time the tablets disintegrate completely.

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