Pharma gyan Pandit

Deficiency of Vitamin D

Vitamin D deficiency, or Hypovitaminosis D, can result from inadequate nutritional intake of vitamin D, inadequate sunlight exposure (in particular sunlight with adequate ultraviolet B rays), disorders limiting vitamin D absorption, and conditions impairing vitamin D conversion into active metabolites—including certain liver, kidney, and hereditary disorders. Deficiency impairs bone mineralization, leading to bone softening diseases as rickets in children and osteomalacia and osteoporosis in adults. Rickets, a childhood disease characterized by impeded growth and deformity of the long bones. The earliest sign of subclinical vitamin D deficiency is craniotabes, abnormal softening or thinning of the skull.