Pharma gyan Pandit

Drug interactions of Vitamin K

Antibiotics -- Antibiotics, especially cephalosporins, reduce the absorption of vitamin K in the body. It lower levels of vitamin K because these drugs kill not only harmful bacteria but also the bacteria that make vitamin K.

1.    Cefamandole

2.    Cefoperazone

3.    Cefmetazole

4.    Cefotetan

Phenytoin -- Taking anticonvulsants (phenytoin) during pregnancy or while breastfeeding may lower vitamin K in newborns.

Warfarin -- Vitamin K blocks the effects of the blood-thinning medication warfarin, so that it doesn’t work. You should not take vitamin K, or eat foods containing high amounts of vitamin K, while you are taking warfarin.

Orlistat and Olestra -- Orlistat, a medication used for weight loss, and olestra, a substance added to some foods, lowers the amount of fat you body can absorb. Because vitamin K is a fat-soluble vitamin, these medications may also lower levels of vitamin K.

Cholesterol-lowering Drugs -- Bile acid sequestrants, used to reduce cholesterol, reduce how much fat your body absorbs and may also reduce absorption of fat-soluble vitamins.