Mechanism Theories of enzymes:
The Lock & Key
theory describe a situation where the substrate fits perfectly into the
enzyme’s activity site. The activity site is simply the location of the enzyme
where the substrate docks.
The Induced Fit model
begins with an enzyme activity site which does not exactly fit the substrate,
but is stretched to accommodate the substrate.
This second theory gives a more flexible
image of an enzyme than the first.
The ability for an
enzyme to dock and undock molecules is essential in increasing the rate of the reactions.
This turnover number the number of substrate molecules the enzyme is able to
act on in one minute. This turnover number has been standardized by the chemical
community into the enzyme international number. Which is the number of
catalytic conversions per minute of 1 micro mole of substrate, under specific
conditions of temperature and pH.
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