Friday 2 December 2016

Cofactors:

All enzymes are proteins.  But sometimes, for a protein to function it requires the assistance of another molecule or ion, a cofactor.  Cofactors are normally thought of as metal ions, but when this cofactor is a small organic molecule it is named a coenzyme.  The magnesium ion is required for the body to use glucose-phosphate compounds.  Coenzymes are also called vitamins.  Further yet, some coenzymes themselves must by accompanied by another organic molecule to function properly.  If an enzyme requires a cofactor the protein is named apoenzyme until the cofactor has been added.

VITAMIN
FUNCTION
DEFICIENCY SYMPTOM
WATER SOLUBLE


Ascorbic Acid (C)
Hydroxylases
Scurvy - connective tissue
Thiamine (B1)
reductases
Beriberi-fatigue
Riboflavin (B2)
reductases (Flavine)
Skin disease
Pyridoxine (B6)
Aminotransferases
Anemia
Niacin
reductases (NAD)
Pellagra -skin and nerve
Folic Acid (M)
Methyltransferases
Anemia
Vitamin B12
Isomerase
Anemia
Pantothenic Acid
Acyltransferase (CoA)
Weight Loss
Biotin (H)
Carboxylases
Dermatitis
FAT SOLUBLE


Vitamin A
Vision and Cell Differentiation
Night Blindness
Vitamin D
Calcium Metabolism
Rickets - bone problems
Vitamin E
Antioxidant
Fragile cell membranes
Vitamin K
Blood Clotting
Delayed blood clotting

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