Classification of
Antiulcer agents
1. Tranquilizers, which decrease vagal activity.
2. Anticholinergics, which decrease acetylcholine by blocking
the cholinergic receptors.
3. Antacids, which neutralize gastric acid.
4. H2 blockers, which block the H2 receptor.
5. PPIs, which inhibit gastric acid secretion, regardless of
acetylcholine or histamine release;
6. The pepsin inhibitor sucralfate.
7. The prostaglandin E1 analogue misoprostol, which inhibits
gastric acid secretion and protects the mucosa.
Currently, tranquilizers and anticholinergics are used
infrequently due to potential adverse effects and much more effective drugs on
the market.
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