Because it is in buffer system of extracellular fluid, this
results from a number of factors:
1. There is considerably more bicarbonate present in
extracellular fluid than any other buffer component.
2. There is a limitless supply of carbon dioxide.
3. Physiological mechanisms operate to maintain the
extracellular pH function by controlling fluid.
4. The bicarbonate –carbonic acid buffer system operates in
conjunction with haemoglobin.
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