Saturday 13 May 2017

Drugs for Peptic Ulcer
1. Gastric acid secretion inhibitors
(a) H2 antihistamines: Cimetidine, Ranitidine,Famotidine, Roxatidine
(b) Proton pump inhibitors: Omeprazole, Esomeprazole, Lansoprazole, Pantoprazole, S (-) Pantoprazole, Rabeprazole, Dexrabeprazole.
(c) Anticholinergics: Pirenzepine, Propantheline, Oxyphenonium
(d) Prostaglandin analogues: Misoprostol
2. Gastric acid neutralizers (Antacids)
(a) Systemic: Sodium bicarbonate, Sod. citrate
(b) Nonsystemic: Magnesium hydroxide Mag. trisilicate, Aluminium hydroxide gel, Magaldrate, Calcium carbonate
3. Ulcer protectives
Sucralfate, Colloidal bismuth subcitrate (CBS)
4. Anti-H. pylori drugs

Amoxicillin, Clarithromycin, Metronidazole, Tinidazole, Tetracycline

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